CIPRODEX (ciprofloxacin 0.3% and dexamethasone 0.1%) Sterile Otic Suspension contains the quinolone antimicrobial, ciprofloxacin hydrochloride, combined with the corticosteroid, dexamethasone, in a sterile, preserved suspension for otic use. Ciprodex ear drops is a prescription medicine used to treat middle ear infections inside the ear (also called otitis media), and infections of the outer ear canal (also called otitis externa). Ciprofloxacin and dexamethasone combination ear drops is used to treat ear infections, such as acute otitis externa and acute otitis media. Otitis externa, also known as swimmer's ear, is an infection of the outer ear canal caused by bacteria. Ciprodex is an ear drop suspension that contains ciprofloxacin (a fluoroquinolone antibiotic) and dexamethasone (a corticosteroid). It's used to treat middle and outer ear infections in people ages 6 years and older. The dosage is 4 drops twice a day, typically for 7 days. CIPRODEX® (ciprofloxacin 0.3% and dexamethasone 0.1%) Sterile Otic Suspension contains the synthetic broad-spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, dexamethasone, in a sterile, preserved suspension for otic use. Medscape - Otitis externa dosing for Ciprodex (dexamethasone-ciprofloxacin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and. Ciprofloxacin/dexamethasone contains two medicines that work in different ways to treat ear infections. Ciprofloxacin is an antibiotic that kills certain types of bacteria by making them less. CIPRODEX is a prescription medicine used in the ear only (otic use) that contains 2 medicines, a quinolone antibiotic medicine called ciprofloxacin and a corticosteroid medicine called dexamethasone. How often should CIPRODEX® Otic be given? CIPRODEX® Otic ear drops should be given 2 times each day (about 12 hours apart, for example, 8 AM and 8 PM) in each infected ear unless the doctor has instructed otherwise. The best times to use the ear drops are in the morning and at night. CIPRODEX OTIC prescription and dosage information for physicians and health care professionals. Pharmacology, adverse reactions, warnings, and CIPRODEX OTICside effects.